*Research Associate/Senior Research Associate - Peptide/High Potent APIs (HPAPI)/Organic/Antibody Drug Conjugation (ADC) o2h Group

Peptide Chemist: • Plan and execute solid-phase and solution-phase peptide synthesis (SPPS/LPPS) using automated synthesizers such as Syro and CEM Liberty Blue • Independently handle peptide synthesis across scales from gram to 1 kg, with troubleshooting abilities • Purify and characterize peptides using preparative HPLC, analytical HPLC, LC-MS, and MS • Operate, calibrate, and maintain lab equipment to keep synthesis workflows running smoothly • Maintain compliance with laboratory safety and SHE (Safety, Health & Environment) standards • Review relevant literature to inform synthetic strategy and troubleshooting approaches • Keep accurate, timely...

*Scientist - DMPK o2h Group

• Perform routine in vitro ADME assays such as microsomal stability, plasma stability, solubility, permeability, CYP inhibition, and plasma protein binding assays • Develop, optimise, and execute analytical methods using LC-MS/MS and complementary detection modalities (absorbance/fluorescence-based assays) • Support development and validation of new ADME assays to expand the group’s scientific capabilities • Process and analyse experimental data using GraphPad Prism, MS Excel, and mass spectrometry software platforms (e.g., Sciex) • Prepare clear experimental documentation, study summaries, and reports for internal teams and external collaborators • Coordinate wi...

*Associate Research Scientist/Scientist - Biology o2h Group

• Ph.D with Postodoctoral or Masters with 5+ years of hands-on experience in cell-based assay development and troubleshooting skills; ability to handle different plate formats for small molecule screening  • Reporting to senior team leader, work with a group of in vitro assay biologists, learning and coaching group members to improve skills and productivity  • Independently design, conduct, optimize and proactively troubleshoot assays  • Develop, optimize and validate biochemical and cell-based assay platforms for the hit identification, lead optimization and functional characterization of small molecules  • Work on the bench implementing state-of-the-art technologi...

*Senior/Principal Scientist - Analytical o2h Group

Senior/Principal Scientist: • 10+ years of experience in CRO with hands-on experience in LCMS/Prep. HPLC/NMR/HPLC method development for NCE Molecules in analytical scale. • Proficiency in various purification techniques. • Strong understanding of various column chemistries. • Skilled in troubleshooting, instrument maintenance, and calibration. • Lead, train, coach, and mentor a team of motivated young scientists. • Provide guidance and support across different shifts to ensure the timely delivery of analytical data to the chemistry team. • Ready to work closely with motivated scientists, fostering a collaborative and performance-driven environm...